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Ubiquinol as a support therapy in the treatment of autism

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Monday, 03 August 2015 16:26
Ubiquinol as a support therapy in the treatment of autism
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A Ubiquinol-based supplement may help to attenuate behavioural problems in autistic children, according to the results of a current study by the Coménius University in Bratislava. Ubiquinol, the active form of Coenzyme Q10, improves the supply of energy to human cells and, as a powerful anti-oxidant, protects the phospholipids in cell membranes from peroxidation.


For the purposes of this study (1), twenty-four autistic children aged from three to six received a Ubiquinol-based food supplement over a period of three months: 50 mg per day for the first week and thereafter 100 mg per day. The aim of the study was, among other items, to perfect a new diagnostic test and to analyse what effect Ubiquinol might have on the behaviour of autistic children and on peroxidation. When the concentration of total Coenzyme Q10 in the plasma exceeded 2.15 mg/l, the well-known typical symptoms showed a significant improvement. After taking Ubiquinol, the level of Coenzyme Q10 in the plasma rose from an ineffective 0.55 mg/l to 2.6 mg/l. Such values are more easily attained using active Ubiquinol than with the standard Coenzyme Q10. The significant improvements were observed for troubles in sleeping (for 34% of the children), ability to play with friends (42%), verbal communication (21%) and the desire to eat (17%). This assessment shows that the concentration of total Coenzyme Q10 in blood plasma and lipidic oxidation may be capable of being used as important bio-markers in any Ubiquinol-based therapy with autistic children.

Autism is a deep-seated disorder in neurological development for which there is no known cure. Specific therapies can however be used to attenuate the symptoms. A Ubiquinol-based supplement is a promising starting point. As a naturally occurring substance it has been extensively studied and has no known side effects. With this particular study, for the first time, the importance of Ubiquinol in the treatment of autistic children has been demonstrated. Further studies with a much larger sample of children will be necessary to confirm these findings and to be able to formulate any therapeutic recommendations.
(1) Anna Gvozdjáková et al.: “Ubiquinol Improves Symptoms in Children with Autism”, Oxidative Medicine and Cellular Longevity Volume 2014 (2014), Article ID 798957.

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